| Netherlands U21 League | 2022/02/26 14:00 | FC Twente/Heracles Academie U21 v Heerenveen U21 | D | 1-1 |
| Netherlands U21 League | 2022/02/12 15:00 | Almere City FC U21 v FC Twente/Heracles Academie U21 | W | 1-2 |
| Netherlands U21 League | 2021/12/18 14:00 | FC Groningen U21 v FC Twente/Heracles Academie U21 | L | 6-1 |
| Netherlands U21 League | 2021/12/04 13:30 | FC Twente/Heracles Academie U21 v NEC U21 | D | 1-1 |
| Netherlands U21 League | 2021/11/20 13:45 | NAC U21 v FC Twente/Heracles Academie U21 | L | 3-1 |
| Netherlands U21 League | 2021/11/06 14:15 | FC Twente/Heracles Academie U21 v Feyenoord U21 | L | 0-3 |
| Netherlands U21 League | 2021/10/30 13:00 | ADO Den Haag U21 v FC Twente/Heracles Academie U21 | L | 3-1 |
| Netherlands U21 League | 2021/10/23 12:30 | Heerenveen U21 v FC Twente/Heracles Academie U21 | W | 0-3 |
| Netherlands U21 League | 2022/05/14 12:30 | FC Emmen U21 v Vitesse U21 | L | 2-1 |
| Netherlands U21 League | 2022/02/05 13:30 | Vitesse U21 v FC Emmen U21 | D | 2-2 |
| 클럽 친선 경기 | 2021/11/12 13:00 | Vitesse U21 v ADO Den Haag U21 | W | 7-0 |
| Netherlands U21 League | 2021/11/05 15:00 | Vitesse U21 v Excelsior Rotterdam U21 | D | 0-0 |